TY - JOUR ID - 120305 TI - Assessment of Anti-Streptolysin-O Titre in Healthy School-Age Children in Alexandria Governorate JO - International Journal of Medical Arts JA - IJMA LA - en SN - 2636-4174 AU - Abdou, Aziza Abdelaziz AU - Zannoun, Mohamed Abdel Salam AU - El Ghanam, Magdy Zaki AD - Department of Pediatrics, Damietta Faculty of medicine, Al-Azhar University, Egypt AD - Department of Clinical Pathology, Damietta Faculty of medicine, Al-Azhar University, Egypt Y1 - 2021 PY - 2021 VL - 3 IS - 1 SP - 995 EP - 1000 KW - Group-A Streptococci [GAS] KW - Anti-streptolysin O [ASO] KW - Upper limit of normal KW - children KW - Alexandria-Governorate DO - 10.21608/ijma.2020.42462.1163 N2 - Background: Serology of streptococcal [GAS] group-A is used for post-streptococcal disease diagnoses, such as acute rheumatic fever, and occasionally for streptococcal pharyngitis diagnoses. Streptococcal titers vary according to a number of factors, including age and population. In developing countries, where GAS-induced impetigo is rare, the titers in healthy people are low in early childhood, peak in children aged 6 to 15, decrease in late adolescence and early adulthood, and then flatten off afterwards.Aim of the work: To assess Anti streptolysin-O titre in healthy school age children in Alexandria governorate.  Patients and Methods: A prospective study had been performed in Alexandria Governorate and the collected sample were tested in clinical pathology Lab [Al-Azhar University Hospital, Damietta]. A total of 3000 [1540 Males, 1460 Females] serum samples had been collected from children aged 6-15 years, had been tested for Anti-streptolysin O titer [ASO] by latex. Results: ASO from 100-200 was higher with 1281 [42.7%] followed by Conclusions: We concluded that upper limit of normal [ULN] ASOT is quite high in normal Egyptian children, reaching up to 850.0 IU / ml. Mapping of upper normal levels and associated factors with increased levels could provide a clue for future planning to prevent streptococcal infection and its associated complications. UR - https://ijma.journals.ekb.eg/article_120305.html L1 - https://ijma.journals.ekb.eg/article_120305_1185f6001bcace89642367183b276267.pdf ER -