Background: Better and early prediction of malignant thyroid nodule, and sure differentiation from benign one, is crucial need to decrease the rate of non-indicated surgeries. The aim of the work: To find risk factors and predictors of malignancy in patients with thyroid nodule[s]. Patients and Methods:Fifty patients with thyroid nodule[s] were included. All patients were evaluated by history taking, clinical examination and laboratory investigations. Imaging studies included thyroid ultrasound [US]. All were also submitted to fine needle aspiration cytology [FNAC] before treatment by total or subtotal thyroidectomy. Excised tissues were sent to histopathological analysis. Results:The incidence of malignancy was 22.0%. both benign and malignant groups were comparable as patient characteristics, complaints except the significant increase in cosmetic disfigurement among patients with benign nodules [92.3% vs. 45.5%].Patients with malignant nodules had a significant increase of ill-defined margins, intranodular vascularity and enlarged lymph nodes [72.7%, 63.6% and 72.7% vs 5.1%, 12.8% and 25.6% respectively].Ill-defined margins, enlarged lymph node and high grade in FNAC were the predictors of thyroid malignancy. Conclusion:Predictors of malignant thyroid nodules are ill- defined edges, enlarged lymph node and high grade in FNAC. This helps clinicians to spare more benign cases from surgical interference.
Mohamed Ragab, A., Sayouh, A., Sarhan, A. (2021). Predictors of Malignancy in Thyroid Nodules. International Journal of Medical Arts, 3(2), 1369-1376. doi: 10.21608/ijma.2021.43700.1178
MLA
Abdel Rahman Ahmed Mohamed Ragab; Ahmed Salama Sayouh; Amr Abdel Ghany Sarhan. "Predictors of Malignancy in Thyroid Nodules". International Journal of Medical Arts, 3, 2, 2021, 1369-1376. doi: 10.21608/ijma.2021.43700.1178
HARVARD
Mohamed Ragab, A., Sayouh, A., Sarhan, A. (2021). 'Predictors of Malignancy in Thyroid Nodules', International Journal of Medical Arts, 3(2), pp. 1369-1376. doi: 10.21608/ijma.2021.43700.1178
VANCOUVER
Mohamed Ragab, A., Sayouh, A., Sarhan, A. Predictors of Malignancy in Thyroid Nodules. International Journal of Medical Arts, 2021; 3(2): 1369-1376. doi: 10.21608/ijma.2021.43700.1178