Assessment of Suprachoroidal Injection of Triamcinolone Acetonide in Cases of Diabetic Macular Edema

Document Type : Original Article


1 Department of Ophthalmology, Damietta Faculty of Medicine, Al-Azhar University, Egypt

2 Department of Ophthalmology, Faculty of Medicine, Al-Azhar University, Egypt


Background: Diabetic retinopathy [DR] remains one of the main causes of visual reduction in the world. The visual reduction in patients with DR is usually due to diabetic macular edema [DME].Suprachoroidal triamcinolone acetonide injection is a new effective modality used for the management of diabetic macular edema.
The aim of the work: To assess the visual acuity [VA], central macular thickness [CMT] by optical coherence tomography [OCT] and intraocular pressure [IOP] measurement in patients with DME injected with Triamcinolone Acetonide through suprachoroidal space.
Patients and Methods: Forty eyes of 37 patients [18 males and 19 females]] with DME were included and followed-up for 6 months to assess VA, CMT and IOP. Patients were included if they were diagnosed as DME. 
Results: Baseline measurements were logMAR best corrected visual acuity [VA] which was 0.83 ± 0.09, [OCT] which was 422.42 ± 64.1 µm and [IOP] which was 15.25 ± 1.46 mmHg. Post injection measurements of VA during the four points of the follow-up period showed statistically significant improvement. At one-week post-injection,  logMAR VA was 0.82 ± 0.09, at one-month follow-up was 0.72 ± 0.09, at three months was 0.68 ± 0.1, at six months, was 0.62 ± 0.1,. OCT follow-up measurements showed highly significant improvements, which started from the first week post-injection till the end of the follow-up period at six months point. At one week, it measured 391.7 ± 60.6 µm, at one month the measurement was 337.1 ± 54.5 µm, at three months was 302.7 ± 46.5, at six months, was 267.9 ± 40.7.
Conclusion: Injection of TA to the suprachoroidal space in DME, was well tolerated without any serious ocular adverse events and produced significant resolution in CST and significant improvement in BCVA.


Main Subjects