Background: Alopecia areata is an autoimmune disorder caused by a breakdown in the follicular immune privilege system, resulting in non-scarring hair loss. Many therapeutic options have been tested with variable results. Aim of the work: To assess the efficacy of trichloroacetic acid [TCA] 35% in patients of alopecia areata. Patients and Methods: This prospective cross-sectional study included 40 patients recruited from department of dermatology and venereology, Al-Hussein hospital. Every patient was treated by 3 sessions of TCA 35% with one-month intervals. The assessment was done by clinical, trichoscopy, and histopathological examination. Results: The study included 40 patients, 22 males [55%] and18 females [45%]. The mean age of studied patients was 25.6 ± 8.6 years with a minimum age of 16 years and a maximum age of 50 years. The duration of the disease ranged between 2 months and 10 years with a mean duration of 2.7 ± 2.5 years. Thirty patients [75%] showed improvement at the end of TCA sessions. Conclusion: Based on our findings, topical application of TCA 35% is a safe and effective treatment option for patients with alopecia areata. Moreover, it can be used in wide areas of the scalp and cases of alopecia totalis.
Anter, H., Zaky, A., Nouh, A., & El-Khalawany, M. (2023). Efficacy of Trichloroacetic Acid in Patients with Alopecia Areata: A Clinico-Histopathological Study. International Journal of Medical Arts, 5(2), 3033-3038. doi: 10.21608/ijma.2023.197060.1634
MLA
Hossam Mamdouh Anter; Amr M. Zaky; Ahmed H. Nouh; Mohamed El-Khalawany. "Efficacy of Trichloroacetic Acid in Patients with Alopecia Areata: A Clinico-Histopathological Study". International Journal of Medical Arts, 5, 2, 2023, 3033-3038. doi: 10.21608/ijma.2023.197060.1634
HARVARD
Anter, H., Zaky, A., Nouh, A., El-Khalawany, M. (2023). 'Efficacy of Trichloroacetic Acid in Patients with Alopecia Areata: A Clinico-Histopathological Study', International Journal of Medical Arts, 5(2), pp. 3033-3038. doi: 10.21608/ijma.2023.197060.1634
VANCOUVER
Anter, H., Zaky, A., Nouh, A., El-Khalawany, M. Efficacy of Trichloroacetic Acid in Patients with Alopecia Areata: A Clinico-Histopathological Study. International Journal of Medical Arts, 2023; 5(2): 3033-3038. doi: 10.21608/ijma.2023.197060.1634