Background: The outcome of spontaneous vaginal birth is improved using analgesics during the three phases of labour. Both pharmaceutical and non-pharmaceutical approaches have been tried. Therefore, this study aimed to compare parenteral ketamine and tramadol regarding their analgesic effect and maternal and labor outcome. Patients and Methods: This randomized clinical trial was conducted on 100 primigravida and multigravida women. The study population was randomized into two equal groups; ketamine group: received low dose ketamine 0.4 mg/kg body weight intravenous [IV] slowly over 30-60 seconds with maintenance dose at the rate of 1 mg/min in normal saline after 30 min of induction dose using an infusion pump and the tramadol group: 1 mg/kg iv slowly for 5-10 minutes then after 30 min we start maintenance by IV Tramadol 0.3 mg /kg/hr. Results: Ketamine significantly decreased the time of onset analgesia [p=0.036] and VAS [p=0.002] than tramadol. Ketamine has a significant advance in patient satisfaction than tramadol. The duration of all 3 stages of labor, Apgar score after 1 min, Apgar score after 5 min, and the percentage of maternal complications did not exhibit any significant change between both groups. Conclusion: In spontaneous vaginal delivery, ketamine and tramadol are considered safe drugs with low complications and similar Apgar scores after 1 min and also after 5 min with superiority of ketamine than tramadol regarding the earlier time of onset analgesia, lower VAS score and better patient satisfaction.
Elsheshtawy, K. (2023). Ketamine versus Tramadol for Analgesia in Spontaneous Vaginal Delivery: A Randomized Clinical Trial. International Journal of Medical Arts, 5(8), 3495-3500. doi: 10.21608/ijma.2023.214270.1696
MLA
Khaled Elsheshtawy. "Ketamine versus Tramadol for Analgesia in Spontaneous Vaginal Delivery: A Randomized Clinical Trial". International Journal of Medical Arts, 5, 8, 2023, 3495-3500. doi: 10.21608/ijma.2023.214270.1696
HARVARD
Elsheshtawy, K. (2023). 'Ketamine versus Tramadol for Analgesia in Spontaneous Vaginal Delivery: A Randomized Clinical Trial', International Journal of Medical Arts, 5(8), pp. 3495-3500. doi: 10.21608/ijma.2023.214270.1696
VANCOUVER
Elsheshtawy, K. Ketamine versus Tramadol for Analgesia in Spontaneous Vaginal Delivery: A Randomized Clinical Trial. International Journal of Medical Arts, 2023; 5(8): 3495-3500. doi: 10.21608/ijma.2023.214270.1696