Rates and Risk Factors of Acute Ischemic Stroke Mortality [A Multi-Center Prospective Cohort Study]

Document Type : Original Article

Authors

Department of Neurology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt

Abstract

Background: Treatment of stroke had recent advances. However, and irrespective of these advances, it remains the second commonest cause of death and the chief cause of disability all over the world.
The Aim of the work: To estimate the incidence and risk factors associated with in- hospital ischemic stroke mortality.
Patients and Methods: In the prospective cohort study, 128 patients who had ischemic stroke. The diagnosis was built on the clinical and radiological basis. They were selected from the emergency department or stroke unit, Al-Azhar University Hospitals, between the start of December 2022 to the end of May 2023. Patients who survived were compared with the subgroup with lethal outcome regarding different factors.
Results: The in-hospital mortality was reported in 11 patients [8.6%]. Mortality was significantly associated with arterial fibrillation, older age, progression of stroke, hemorrhagic transformation, edema, respiratory and gastrointestinal [GIT] complications. In addition, mortality was associated with higher assessment scores. Respiratory and GIT complications and atrial fibrillation remains the significantly associated with mortality after adjusting for all factors.
Conclusion: The mortality rate is comparable with reported data from some developed and developing countries. Development of hemorrhagic transformation, cerebral edema, pneumonia, GIT bleeding at admission appears to be associated with in-hospital mortality.

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