Impact of Chronic Urticaria on Patients’ Quality of Life in Damietta Governorate

Document Type : Original Article

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Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Al-Azhar University, Damietta, Egypt.

Abstract

Background: Chronic urticaria is characterized by the presence of recurrent wheel, with or without angioedema, occurring at least twice a week for longer than 6 weeks.
Aim of the Work: This study aimed to evaluate the impact of chronic urticaria on patients’ quality of life and to assess its correlation with the severity of the disease in Damietta governorate.
Patients and Methods: This was a randomized clinical trial that included 200 patients with chronic urticarial in dermatology outpatient clinic at Damietta Faculty of Medicine from June 2023 to June 2024. All were evaluated by urticaria activity score and chronic urticaria quality of life questionnaire.
Results: Over half of patients [54%] experience work and physical activity limitations, while 46% experience sleep and free time limitations. Most patients [70%] have limitations in social relationships, 60% in eating, and 60% in falling asleep. Additionally, 76% wake up at night, 56% are tired during the day, 66% have difficulties concentrating, and 58% often feel nervous. These limitations can impact various aspects of daily life, including sleep, concentration, and overall well-being. There was a statistically significant difference between urticaria activity score and chronic urticaria quality of life questionnaire as the mean of CuQoL was higher among patients with severe urticaria in comparison to patients with mild urticarial.
Conclusion: Chronic urticaria significantly impacts patients' quality of life, particularly in those with autoimmune urticaria. The study highlights the importance of evaluating quality of life to assess disease progression and treatment efficacy. The CuQOL, a reliable and cost-effective tool, is deemed valid for research and clinical practice.

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