Evaluation of Tp-e / QT Ratio as a Predictor of Hospital Course in Patients with Decompensated Heart Failure

Document Type : Original Article

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Department of Cardiovascular Medicine, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.

Abstract

Background: Heart failure [HF] is a clinical syndrome characterized by breathlessness, fatigue, ankle swelling, and signs such as peripheral edema, pulmonary crackles, and elevated jugular venous pressure.
The aim of the work: This work aimed to assess the utility of the Tp-e/QT ratio as a prognostic marker for the clinical course of cases hospitalized with decompensated HF.
Patients and Methods: This prospective observational research included 100 patients diagnosed with HF with diminished ejection fraction [EF], defined as a left ventricular EF below 40%.
Results: Tp-e intervals, Tp-e/QTc and Tp-e/QT ratios were significantly elevated in cases who developed arrhythmias. These electrocardiographic parameters were also significantly elevated in cases whose hospital stay exceeded one week.
Conclusion: Non-survivors exhibited elevated rates of valvular heart disease, diminished EF, elevated LDL titres, and elevated QTc, QT interval, Tp-e, and Tp-e/QT ratios. Careful monitoring of these parameters, particularly ECG markers [Tp-e/QT] and hemodynamic status, could be vital for effective risk stratification and optimizing treatment strategies in cases with HF.

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