The Impact of Intravenous Glucose Administration on Maintenance of Body Temperature during Total Knee Replacement under Spinal Anesthesia in Geriatric Patients: A Randomized Controlled Trial

Document Type : Original Article

Authors

1 Department of anesthesia, Intensive Care and Pain Management, Faculty of Medicine, Mansoura University, Mansoura , Egypt

2 Consultant Anesthetist, Dubai Health Authority, Dubai, UAE.

Abstract

Background: Total knee replacement [TKR], more common in the elderly, can cause inadvertent perioperative hypothermia, which can be prevented. Preoperative intravenous [IV] glucose may minimize heat loss by increasing metabolism and heat generation.
The aim of the work: This study examined how preoperative IV 10% glucose affected body temperature in elderly TKR patients under spinal anesthesia [SA].
Patients and Methods: This randomized controlled trial involved 78 ASA I-II elderly patients scheduled for elective TKR under SA. Eligible patients were randomly allocated into two equal groups: group A received a 10% glucose infusion, while group B received 0.9% normal saline [NS], administered 6 hours before surgery. The occurrence of hypothermia was the primary outcome.
Results: At the end of surgery, group B exhibited a notable significant lower value of core temperature [p<0.001] with a non-significant alteration in surface temperature [p=0.087] than group A. Group B experienced more adverse effects compared to group A with statistically significant differences, particularly hypothermia [p= 0.040] and shivering [p=0.007].
Conclusion: Elderly individuals undergoing total knee replacement under spinal anesthesia may benefit from a preoperative intravenous infusion of 10% glucose to help control body temperature and avoiding shivering.

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